Factitious Disorder in Crohn's Disease: Recurrent Pancytopenia Caused by Surreptitious Ingestion of 6-Mercaptopurine

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Factitious Disorder in Crohn's Disease: Recurrent Pancytopenia Caused by Surreptitious Ingestion of 6-Mercaptopurine

Factitious disorder is a rare psychiatric illness characterized by the willful and deceptive induction of illness for the purpose of assuming the sick role. It presents a substantial diagnostic challenge, as patients often go to great lengths to conceal their deception. Accordingly, its presence in the full spectrum of gastrointestinal diseases is likely underappreciated. While factitious gastr...

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Pancytopenia caused by iron-dextran.

Pancytopenia after intramuscular iron-dextran treatment occurred in an infant with Down's syndrome. Haematological abnormalities recurred on subsequent challenge. Positive migration inhibiting factor and mast cell degranulation tests support an allergic pathogenesis for the pancytopenia. These side effects have not been reported previously.

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Factitious disorder in adolescence.

Factitious disorder (FD) is defined as a condition in which a person voluntarily produces symptoms or illness and acts as if they are ill without an external gain (1). In the Psychiatric Disorders Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), it is divided into three types as “Factitious disorders with predominantly psychological signs and symptoms”, “Factitious disorders with...

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Media Induced Factitious Disorder by Proxy

Perpetrators of Factitious Disorder by proxy are usually driven by motives such as garnering attention, mobilizing sympathy, acting out anger or controlling others. Widespread media coverage provides an opportunity for fulfilling all these needs. We describe a case of Factitious Disorder by proxy with a rather unusual ocular complaint. Circumstantial evidence indicates that the presentation may...

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Enhancement of Antibody Synthesis by 6-mercaptopurine

The administration of 6-MP to rabbits led to either suppression or enhancement of antibody production, depending on when the drug was given in relation to the antigenic challenge. Maximum enhancement of antibody synthesis was found when a small dose of BGG was administered 5 days after the last dose of a 1 wk course of 6-MP. There were no indications that the macrophage system or immunological ...

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ژورنال

عنوان ژورنال: Case Reports in Gastroenterology

سال: 2015

ISSN: 1662-0631

DOI: 10.1159/000382073